I'll just throw out a few that always stay with me for some reason...
"All I can get" - Paul Newman in Slapshot after being told he sucks dick.
"We could kill everybody" - Rocko in The Boondock Saints.
"You're a fucking inanimate object" - Ralph Fiennes in In Bruges.
"He's not Judge Judy and executioner!" - Nick Frost in Hot Fuzz.
"I'm the bad guy?" - Michael Douglas in Going Down. Uh, I mean Falling Down.
"Please don't shoot at the thermonuclear weapons!" - John Travolta in Broken Arrow.
"Whim of a madman! I like that" - Dennis Hopper in Speed.
Everything in Young Guns one and two.
“Today a young man on acid realized that all matter is merely energy condensed to a slow vibration, that we are all one consciousness experiencing itself subjectively, there is no such thing as death, life is only a dream, and we are the imagination of ourselves.” – Bill Hicks